Cancrum oris – Discuss Dentistry https://demo.discussdentistry.com/forums/topic/cancrum-oris/feed/ Mon, 17 Nov 2025 20:40:28 +0000 https://bbpress.org/?v=2.6.12 en-US https://demo.discussdentistry.com/forums/topic/cancrum-oris/#post-17170 <![CDATA[Re: Cancrum oris]]> https://demo.discussdentistry.com/forums/topic/cancrum-oris/#post-17170 Tue, 03 May 2011 10:30:12 +0000 ANTIBIOTIC REGIME FOR TREATMENT

most authors recommend penicillin + metronidazole. Agents used empirically to cover predominant organisms. Use tissue/blood cxs to tailor regimen. Rx for at least 14 days.
* Preferred: penicillin G 2-4 million U IV q4h + metronidazole (Flagyl) 500mg IV q6-12h.
* Alternative: ampicillin/sulbactam (Unasyn) 3.0g IV q6h.
* PCN allergy: clindamycin (Cleocin) 600mg IV q8h.
* Note: use of systemic abx in HIV pts may cause candidal overgrowth requiring additional antifungal coverage. Consider Nystatin rinses 5ml four times a day or fluconazole 200mg PO once daily.

        

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